Dr. med. Nico Leibig

• 2005 – 2012 Humanmedizinstudium an der Albert-Ludwig-Universität Freiburg im Breisgau;  mit Praktisches Jahr Tertialen am Tampa General Hospital, University of South Florida, USA und am Kantonspital Liestal, Universität Basel, Schweiz
• 2012 – 2016 Assistenzarzt an der Klinik für Hand, Plastische und Rekonstruktive Chirurgie – Schwerbrandverletztenzentrum- der BG Unfallklinik Ludwigshafen
• 2016 – 2020 Assistenz- und Funktionsoberarzt an der Klinik für Plastische und Handchirurgie Universitätsklinik Freiburg
• 2020 – 2021 Oberarzt an dem Zentrum für Hand- und Plastische Chirurgie der Orthopädischen Klinik Markgröningen
• 2021 – 2026 Oberarzt und Co-Bereichsleiter für Handchirurgie an der Klinik für Plastische und Handchirurgie Universitätsklinik Freiburg
• Seit 2025 Mitglied der Leitungsgruppe der S3-Leitlinie „Behandlung der Rhizarthrose“
• Seit 2026 Tätigkeit am Orthopaedicum Freiburg und dem Aestheticum Freiburg

• 2019 Facharzt für Plastische und Ästhetische Chirurgie
• 2020 Zusatzbezeichnung Handchirurgie
• 2025 Fellow of the European Board of Hand Surgery

• 2011 „Die Wirkung von Rho-Inhibition und Interleukin 10 auf die Regenerationsfähigkeit des peripheren Nervensystems.“ in der Abteilung für Plastische und Handchirurgie Universitätsklinik Freiburg

Hohenstein AA., Nguyen CT., Zeller J., Fricke M, Zajonc H., Eisenhardt SU., Leibig N.
Therapie der Skaphoidpseudarthrose – Behandlungsalgorithmus und Analyse der Durchbauungsrate bei autologer Rekonstruktion
Handchir Mikrochir Plast Chir. 2025 Sep;57(5):335-343. doi: 10.1055/a-2685-3879. Epub 2025 Oct 22.

Hohenstein AA., Nguyen CT., Zeller J., Fricke M, Zajonc H., Eisenhardt SU., Leibig N.
WALANT in hand trauma surgery: safety and efficacy
Hand (N Y). 2026 Apr 30:15589447261437818. doi: 10.1177/15589447261437818. Online ahead of print.PMID: 42059309

Nguyen CT., Hohenstein AA., Zajonc H., Eisenhardt SU., Leibig N.
All-dorsal Technique for Scapholunate Ligament Reconstruction: Functional and Radiological Outcome
J Hand Surg Eur Vol. 2026 Mar 11:17531934261428319. doi: 10.1177/17531934261428319. Online ahead of print. PMID: 41808659

Kollar B., Ederer N., Fricke M., Leibig N., Weiss J.B.W., Eisenhardt SU., The Artificial
Intelligence-Derived Emotionality State Score Correlates with Layperson Assessment and Objective Measurements of Facial Reanimation Outcomes
Plast Reconstr Surg. 2026 Mar 26. doi: 10.1097/PRS.0000000000013072. Online ahead of print. PMID: 41885556

Leibig, N., Stark, G. B., Zajonc, H., Frick, M., Kiritsi, D., & Lampert, F. Autologous skin micro-grafts and allogenic skin allograft for mitten hand deformity treatment in epidermolysis bullosa.
International Journal of Research in Dermatology, 2022 8(2), 192.

Horner VK, Schneider L, Leibig N, Zeller J, Kiefer J, Eisenhardt SU An Analysis of the Implantable Doppler Probe for Postoperative Free-Flap Monitoring and Risk Factor Analysis for Revision Surgery in Facial Reanimation Surgery
Facial Plast Surg Aesthet Med. 2022 Sep- Oct;24(5):345-351.

Runkel A, Bonaventura B, Sundermann B, Zajonc B, Eisenhardt SU, Leibig N Risk factors in distal interphalangeal joint arthrodesis in the hand: a retrospective study of 173 cases
J Hand Surg Eur Vol. 2022 Oct;47(9):907-914.

Leibig N, Lampert FM, Haerle M
Ulnocarpal Impaction
Hand Clinics 2021 Nov;37(4):553-562.

Halm D*, Leibig N*, Martens J, Stark, G.B., Gross T Zimmermann S, Finkenzeller G, Lampert FM
Direct comparison of the immunogenicity of major histocompatibility complex-I and -II deficient mesenchymal stem cells in vivo
Biological Chemistry 2021 Feb 5;402(6):693-702.

Leibig N, , Stark GB, Zajonc H, Frick M, Kiritsi D, Lampert FM
Autologous skin micrografts and allogenic skin allograft for mitten hand deformity treatment in epidermolysis bullosa
IntJResDermatol VOL. 8 NO. 2 (2022): MARCH-APRIL 2022

Hernekamp F, Leibig N, Cordts T, Kremer T, Kneser U
Revisionary soft tissue reconstruction of posterior midline defects after spinal surgery-plastic reconstructive options including perforator flaps
J Spine Surg. 2021 Sep;7(3):364-375.

Leibig N, Ha-Phuoc A, Stark GB, Schmelzeisen R, Metzger MC, Eisenhardt SU, Voss PJ.
Retrospective evaluation of diagnostic accuracy of free flap monitoring with the Cook- Swartz-Doppler probe in head and neck reconstruction.
J Craniomaxillofac Surg. 2019 Dec;47(12):1973-1979.

Leibig N, Wietbrock JO, Bigdeli AK, Horch RE, Kremer T, Kneser U, Schmidt VJ
Flow induced Axial Vascularization: The Arteriovenous Loop in Angiogenesis and Tissue Engineering [review]
Plast Reconstr Surg. 2016 Oct;138(4):825-35.

Leibig N, Boyle V, Kraus D, Stark GB, Penna V
C3 Toxin and Poly-DL-Lactide-epsilon-Caprolactone Conduits in the Critically Damaged Peripheral Nervous System: A Combined Therapeutic Approach.
Ann Plast Surg. 2015 Mar;74(3):350-3.

Leibig N, Boyle V, Kraus D, Stark GB, Penna V
IL10 and Poly-DL-lactide-ɛ-caprolactone Conduits in Critical Size Nerve Defect Bridging – An Experimental Study
Microsurgery. 2016 Jul;36(5):410-416.

Leibig N, Kneser U, Bickert B
Die Replantation
OP-Journal2015 2:86-92

Leibig N, Hirche C, Schmidt VJ, Bigdeli AK, Kneser U, Kremer T
Necrotizing Fasciitis after Central Venous Catheter Placement.
Surg Infect (Larchmt). 2014 Dec;15(6):850-2.

Schmidt VJ, Wietbrock JO, Leibig N, Hernekamp JF, Henn D, Radu CA, Kneser U.
Haemodynamically stimulated and in vivo generated axially vascularized soft-tissue free flaps for closure of complex defects: Evaluation in a small animal model.
J Tissue Eng Regen Med. 2018 Mar;12(3):622-632.

Schmidt VJ, Wietbrock JO, Leibig N, Gloe T, Henn D, Hernekamp JF, Harhaus L, Kneser U.
Collagen-Elastin and Collagen-Glycosaminoglycan Scaffolds Promote Distinct
Patterns of Matrix Maturation and Axial Vascularization in Arteriovenous Loop-Based Soft Tissue Flaps.
Ann Plast Surg. 2017 Jul;79(1):92-100.

Bigdeli AK, Hernekamp FJ, Neubrech F, Leibig N, Radu C, Gazyakan E, et al. Lower Limb Salvage at any Cost – A Complex Case.
Clin Surg. 2017; 2: 1380.

Schmidt VJ, Hildert JG, Covi JM, Leibig N, Wietbrock JO, Arkudas A, Polykandriotis E, de Wit C, Horch RE, Kneser U Flow increase is decisive to initiate angiogenesis in veins exposed to altered hemodynamics.
PLoS One. 2015 Jan30;10(1):e0117407

Weis C, Covi JM, Hilgert JG, Leibig N, Arkudas A, Horch RE, Kneser U, Schmidt
Automatic quantification of angiogenesis in 2D sections: a precise and timesaving approach.
J Microsc. 2015 Sep;259(3):185-96.

Kraus D, Boyle V, Leibig N, Stark GB, Penna V
The Neuro Spheroid – A novel 3D in vitro for peripheral nerve regeneration.
J Neurosci Methods. 2015 May 15; 246:97-105.

Penna V, Bjoern Stark G, Leibig N, Boyle V, Sakalidou
M Rho- inhibition by local application of c3-toxin for enhancement of axonal sprouting in a rat end-to-side nerve repair model.
Microsurgery. 2012 Mar;32(3):207-12

Sakalidou M, Leibig N, Boyle V, Koulaxouzidis G, Penna V
Interleukin-10 and regeneration in an end-to-side nerve repair model of the rat.
J Peripher Nerv Syst. 2011 Dec;16(4):334-40

• Deutsche Gesellschaft für Handchirurgie – DGH
• Deutsche Gesellschaft für Plastische, Rekonstruktive und Ästhetische Chirurgie – DGPRÄC
• Federation of European Societies for Surgery of the Hand – FESSH